Overview
Chlorpheniramine Syrup 4mg/5ml is a first-generation antihistamine formulated for veterinary use in dogs and cats. It is primarily used to manage allergic reactions, skin irritations, and mild respiratory symptoms. This syrup offers a convenient and palatable alternative to tablets, especially for small animals or those with difficulty swallowing pills. Chlorpheniramine is suitable for pets experiencing seasonal allergies, insect bites, vaccine reactions, or mild anxiety, and is often prescribed off-label under veterinary supervision.
✅ Key Benefits / Features
- Provides effective relief from allergy symptoms such as itching, sneezing, and swelling
- Useful in managing skin conditions like atopic dermatitis and urticaria
- Can be used as a mild sedative for anxious pets
- Syrup formulation allows easy dosing for small or finicky animals
- Fast-acting with effects typically seen within 30–60 minutes
- Suitable for both dogs and cats
🧪 Ingredients
- Active Ingredient: Chlorpheniramine Maleate – 4mg per 5ml
-
Inactive Ingredients (may vary by manufacturer):
- Purified water
- Sorbitol solution
- Glycerin
- Citric acid
- Sodium benzoate
- Flavoring agents
📊 Nutritional Composition / Active Ingredients
| Component |
Quantity per 5ml |
| Chlorpheniramine Maleate |
4 mg |
💊 Uses / Indications
-
Dogs and Cats:
- Allergic skin reactions (e.g., atopic dermatitis, insect bites)
- Urticaria (hives)
- Vaccine or transfusion reactions
- Mild cough or upper respiratory irritation
- Motion sickness or mild anxiety
- Adjunctive therapy for mast cell tumors (histamine control)
🐾 Feeding Instructions / Dosage
-
Dogs:
- 0.2–0.5 mg/kg orally every 8–12 hours
-
Cats:
- 1–4 mg orally every 8–12 hours
-
Administration:
- Shake well before use
- Administer directly into the mouth or mix with food
- Use a calibrated syringe for accurate dosing
- Always follow veterinary guidance for dosage and duration
⚠️ Possible Side Effects
-
Common:
- Drowsiness or mild sedation
- Dry mouth
- Decreased urination
-
Less common:
- Vomiting or diarrhea
- Reduced appetite
- Cats may show paradoxical excitement or agitation
🔄 Drug & Food Interactions
-
May interact with:
- CNS depressants (e.g., acepromazine, opioids)
- Monoamine oxidase inhibitors (MAOIs)
- Phenothiazines
- Avoid human formulations containing decongestants or caffeine
- Stop use at least 2 weeks before allergy testing
⚠️ Precautions
-
Not recommended for:
- Pets with glaucoma, urinary or GI obstruction, hypertension, heart disease, hyperthyroidism, or enlarged prostate
- Use with caution in elderly or debilitated animals
- Monitor for sedation level, appetite changes, and urinary habits
- Store in a cool, dry place and keep out of reach of children
