Overview
Clopidogrel 75mg is an antiplatelet medication used in veterinary medicine to reduce the risk of thromboembolic events in dogs and cats. It works by inhibiting platelet aggregation, thereby preventing the formation of abnormal blood clots that can lead to serious complications such as stroke, aortic thromboembolism, or pulmonary embolism. Clopidogrel is commonly prescribed for pets with underlying cardiac conditions, immune-mediated diseases, or other disorders that predispose them to excessive clotting.
✅ Key Benefits / Features
- Reduces the risk of life-threatening blood clots
- Supports management of thromboembolic diseases in cats and dogs
- Often used in combination with other cardiac or anticoagulant therapies
- Once-daily dosing for convenience
- Proven efficacy in feline aortic thromboembolism and canine immune-mediated hemolytic anemia
🧪 Ingredients
- Active Ingredient: Clopidogrel (as clopidogrel bisulfate) – 75mg per tablet
-
Inactive Ingredients (may vary by manufacturer):
- Hydrogenated castor oil
- Microcrystalline cellulose
- Lactose monohydrate
- Magnesium stearate
- Film-coating agents
📊 Nutritional Composition / Active Ingredients
| Component |
Quantity per Tablet |
| Clopidogrel |
75 mg |
💊 Uses / Indications
-
Cats:
- Prevention and treatment of aortic thromboembolism (FATE)
- Management of thrombotic risk in hypertrophic cardiomyopathy
-
Dogs:
- Adjunct therapy in immune-mediated hemolytic anemia (IMHA)
- Prevention of thromboembolic complications in cardiac or vascular disease
- May also be used in pets with pulmonary hypertension or other clotting disorders
🐾 Feeding Instructions / Dosage
-
Typical Dosage:
- Cats: 18.75 mg (¼ tablet) orally once daily
- Dogs: 1–2 mg/kg orally once daily
-
Administration:
- Can be given with or without food
- Tablets may be split or compounded for accurate dosing in small animals
- Duration of therapy depends on clinical condition and veterinary guidance
⚠️ Possible Side Effects
-
Common:
- Vomiting
- Diarrhea
- Lethargy
-
Rare but serious:
- Bleeding (e.g., bruising, nosebleeds, blood in stool or urine)
- Allergic reactions
- Liver enzyme elevation
- Monitor for signs of bleeding or intolerance during treatment
🔄 Drug & Food Interactions
-
May interact with:
- NSAIDs (e.g., meloxicam, carprofen) – increased bleeding risk
- Anticoagulants (e.g., heparin, warfarin)
- Proton pump inhibitors (e.g., omeprazole) – may reduce clopidogrel efficacy
- No significant food interactions reported
- Always inform your veterinarian of all medications and supplements your pet is receiving
⚠️ Precautions
-
Not recommended for:
- Pets with active bleeding disorders or gastrointestinal ulcers
- Animals with known hypersensitivity to clopidogrel
- Use with caution in pets with liver dysfunction
- Regular monitoring of platelet function and coagulation parameters may be advised
- Store in a cool, dry place and keep out of reach of children
- Human formulations used off-label in veterinary practice; dosing must be determined by a veterinarian
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IMPORTANT NOTICE - THIS IS A PRESCRIPTION ONLY MEDICATION (POM)
POMs are stored and dispensed directly from Ohana Animal Hospital under veterinary supervision.
As required by law, orders for this product will only be processed and delivered after our veterinary team has reviewed your pet's prescription and medical history, who may contact you or your existing vet for more details. Clients are encouraged to Autoship this product to avoid unnecessary delays.
Don't have a prescription? Use our VetCare Rebate program to enjoy $400 off when you renew your prescription.
