Overview
Apo-Enalapril Tablet 20mg is a veterinary formulation of enalapril, an angiotensin-converting enzyme (ACE) inhibitor used to manage cardiovascular and renal conditions in dogs and cats. It is primarily prescribed for the treatment of congestive heart failure, systemic hypertension, and protein-losing nephropathies. This medication is suitable for pets under veterinary care who require long-term support for heart or kidney function.
- ✅ Key Benefits / Features
- Reduces blood pressure by relaxing blood vessels
- Decreases cardiac workload in pets with heart failure
- Minimizes protein loss in urine associated with kidney disease
- Supports renal function and slows progression of chronic kidney conditions
- Can be used in combination with other cardiac or renal medications
- Available in a high-dose 20mg tablet for flexible dosing in larger dogs
🧪 Ingredients
- Active Ingredient: Enalapril Maleate – equivalent to 20mg of Enalapril
- Inactive Ingredients: May include lactose monohydrate, microcrystalline cellulose, magnesium stearate, and other pharmaceutical excipients (varies by manufacturer)
📊 Nutritional Composition / Active Ingredients
| Component |
Quantity per Tablet |
| Enalapril Maleate |
20 mg |
💊 Uses / Indications
-
Dogs:
- Treatment of congestive heart failure due to mitral valve disease or dilated cardiomyopathy
- Management of systemic hypertension
- Control of proteinuria in chronic kidney disease or glomerulonephritis
-
Cats:
- Adjunctive therapy for heart failure
- Management of protein-losing nephropathy and hypertension
🐾 Feeding Instructions / Dosage
-
Dogs:
- Cardiac disease: 0.5 mg/kg orally every 24 hours, may increase to every 12 hours if needed
- Protein-losing nephropathy: 0.25–1 mg/kg orally every 12–24 hours
- Hypertension: 0.5 mg/kg orally every 12 hours
-
Cats:
- 0.25–0.5 mg/kg orally every 12–24 hours
-
Administration:
- Can be given with or without food
- Tablets may be split or compounded for accurate dosing in small animals
- Regular monitoring of blood pressure, renal parameters, and electrolytes is recommended
⚠️ Possible Side Effects
- Hypotension (weakness, disorientation)
- Hyperkalemia
- Azotemia (elevated kidney values)
- Gastrointestinal upset: vomiting, diarrhea, anorexia (rare)
- Lethargy or reduced activity
🔄 Drug & Food Interactions
-
May interact with:
- Potassium-sparing diuretics (e.g., spironolactone) – risk of hyperkalemia
- NSAIDs – may reduce renal perfusion and efficacy
- Diuretics, beta-blockers, vasodilators – increased risk of hypotension
- Safe to use with pimobendan, digoxin, and other cardiac medications under veterinary guidance
⚠️ Precautions
- Not recommended for use in pregnant or lactating animals
- Avoid in pets with hypotension or acute cardiac output failure
- Use cautiously in animals with renal insufficiency or electrolyte imbalances
- Monitor renal function and blood pressure regularly during treatment
- Store in a cool, dry place and keep out of reach of children
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IMPORTANT NOTICE - THIS IS A PRESCRIPTION ONLY MEDICATION (POM)
POMs are stored and dispensed directly from Ohana Animal Hospital under veterinary supervision.
As required by law, orders for this product will only be processed and delivered after our veterinary team has reviewed your pet's prescription and medical history, who may contact you or your existing vet for more details. Clients are encouraged to Autoship this product to avoid unnecessary delays.
Don't have a prescription? Use our VetCare Rebate program to enjoy $400 off when you renew your prescription.
