Overview
Prazon (Prazosin) Tablet 1mg is a veterinary-use alpha-1 adrenergic antagonist prescribed to manage urinary tract disorders and systemic hypertension in dogs and cats. It works by relaxing smooth muscle in blood vessels and the urinary tract, making it easier for pets to pass urine and reducing blood pressure. Prazosin is often used in cases of functional urethral obstruction, prostatic disease, or as adjunctive therapy for congestive heart failure. It is prescribed off-label under veterinary supervision.
✅ Key Benefits / Features
- Relaxes urethral and bladder sphincter muscles to improve urine flow
- Reduces systemic and pulmonary blood pressure
- Supports treatment of congestive heart failure when standard therapies are insufficient
- May help alleviate symptoms associated with prostatic enlargement or spinal disease
- Available in tablet form for accurate dosing
🧪 Ingredients
- Active Ingredient: Prazosin Hydrochloride – 1mg per tablet
-
Inactive Ingredients (may vary by manufacturer):
- Microcrystalline cellulose
- Lactose monohydrate
- Magnesium stearate
- Corn starch
- Film-coating agents
📊 Nutritional Composition / Active Ingredients
| Component |
Quantity per Tablet |
| Prazosin Hydrochloride |
1 mg |
💊 Uses / Indications
-
Dogs:
- Functional urethral obstruction (e.g., reflex dyssynergia)
- Adjunctive treatment for congestive heart failure
- Management of systemic or pulmonary hypertension
-
Cats:
- Urinary tract spasms due to inflammation or obstruction
- Hypertension secondary to chronic kidney disease or hyperthyroidism
- Use in idiopathic cystitis is controversial and may worsen symptoms
🐾 Feeding Instructions / Dosage
-
Dogs:
- Urethral obstruction: 1 mg per 15 kg orally every 12 hours
- Heart failure: 1–2 mg orally every 8–12 hours depending on weight
-
Cats:
- 0.25–1 mg orally every 8–12 hours for 5–7 days, then taper if possible
-
Administration:
- Administer with food to reduce risk of hypotension
- Tablets may be split or compounded for accurate dosing
- Monitor blood pressure and clinical response regularly
⚠️ Possible Side Effects
-
Common:
- Lethargy
- Weakness
- Drowsiness
-
Less common:
- Hypotension (low blood pressure)
- Syncope (fainting)
- Gastrointestinal upset (vomiting, diarrhea)
-
Rare:
- Rapid heartbeat
- Hyperactivity
- Elevated body temperature
🔄 Drug & Food Interactions
-
May interact with:
- Beta-blockers (e.g., propranolol) – increased risk of hypotension
- Diuretics (e.g., furosemide) – additive hypotensive effect
- Calcium-channel blockers – may cause additive blood pressure reduction
- Highly protein-bound drugs (e.g., sulfonamides) – potential displacement interactions
- Administer with food to minimize first-dose hypotensive reactions
⚠️ Precautions
-
Not recommended for:
- Pets with existing hypotension or severe renal failure
-
Use with caution in:
- Animals on multiple antihypertensive agents
- Pregnant or lactating pets (safety not established)
- Monitor blood pressure closely during initiation and dose adjustments
- Store in a cool, dry place away from direct sunlight
- Keep out of reach of children and other animals
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IMPORTANT NOTICE - THIS IS A PRESCRIPTION ONLY MEDICATION (POM)
POMs are stored and dispensed directly from Ohana Animal Hospital under veterinary supervision.
As required by law, orders for this product will only be processed and delivered after our veterinary team has reviewed your pet's prescription and medical history, who may contact you or your existing vet for more details. Clients are encouraged to Autoship this product to avoid unnecessary delays.
Don't have a prescription? Use our VetCare Rebate program to enjoy $400 off when you renew your prescription.
