Overview
Nitrofurantoin 100mg is a veterinary-use antibacterial agent primarily prescribed for the treatment of urinary tract infections (UTIs) in dogs and cats. It is especially effective against multidrug-resistant Gram-positive and Gram-negative bacteria localized in the lower urinary tract. Nitrofurantoin is used off-label in veterinary medicine and is suitable for pets under close veterinary supervision, particularly when first-line antibiotics have failed or resistance is a concern.
✅ Key Benefits / Features
- Targets a broad spectrum of urinary pathogens
- Effective against multidrug-resistant bacteria
- Rapid urinary excretion ensures high concentrations in the bladder
- Low risk of bacterial resistance development
- Suitable for both dogs and cats
- Available in oral tablet form for convenient dosing
🧪 Ingredients
- Active Ingredient: Nitrofurantoin – 100mg per tablet
-
Inactive Ingredients (may vary by manufacturer):
- Lactose monohydrate
- Microcrystalline cellulose
- Magnesium stearate
- Sodium starch glycolate
- Film-coating agents
📊 Nutritional Composition / Active Ingredients
| Component |
Quantity per Tablet |
| Nitrofurantoin |
100 mg |
💊 Uses / Indications
-
Dogs and Cats:
- Treatment of uncomplicated lower urinary tract infections (cystitis)
- Effective against E. coli, Enterococcus spp., and other uropathogens
- Used when culture and sensitivity indicate susceptibility to nitrofurantoin
- Not suitable for systemic infections or pyelonephritis due to limited tissue penetration
🐾 Feeding Instructions / Dosage
-
Typical Dosage:
- Dogs and Cats: 4.4–5 mg/kg orally every 8 hours
-
Administration:
- Must be given with food to enhance absorption and reduce gastrointestinal upset
- Tablets may be split or compounded for accurate dosing in small animals
- Duration of therapy typically ranges from 7–14 days depending on clinical response
- Complete the full course even if symptoms improve early
⚠️ Possible Side Effects
-
Common:
- Vomiting
- Diarrhea
- Loss of appetite
-
Rare but serious:
- Peripheral neuropathy
- Liver toxicity (jaundice, elevated liver enzymes)
- Blood disorders (anemia, thrombocytopenia, leukopenia)
- Allergic reactions (facial swelling, rash, fever)
🔄 Drug & Food Interactions
-
May interact with:
- Fluoroquinolones (antagonistic effect)
- Antimuscarinic drugs (may enhance absorption)
- Spironolactone (may increase risk of hyperkalemia)
- Food delays gastric emptying and improves bioavailability
- Avoid alkalinizing agents which reduce drug efficacy in urine
⚠️ Precautions
-
Not recommended for:
- Pets with significant renal impairment
- Pregnant or lactating animals due to mutagenic potential
- Animals with known hypersensitivity to nitrofurans
- Use with caution in pets with liver disease or diabetes
- Monitor for signs of toxicity during prolonged use
- Store in a cool, dry place and keep out of reach of children
- Not approved for use in food-producing animals
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IMPORTANT NOTICE - THIS IS A PRESCRIPTION ONLY MEDICATION (POM)
POMs are stored and dispensed directly from Ohana Animal Hospital under veterinary supervision.
As required by law, orders for this product will only be processed and delivered after our veterinary team has reviewed your pet's prescription and medical history, who may contact you or your existing vet for more details. Clients are encouraged to Autoship this product to avoid unnecessary delays.
Don't have a prescription? Use our VetCare Rebate program to enjoy $400 off when you renew your prescription.
