Overview

Carbimazole Tablet 5mg is an antithyroid medication used in veterinary medicine to manage hyperthyroidism in cats and, less commonly, in dogs. It works by inhibiting the synthesis of thyroid hormones, helping to restore hormonal balance and reduce the clinical signs associated with an overactive thyroid. Carbimazole is typically prescribed for long-term management or as a preoperative treatment prior to thyroidectomy. It is used off-label under veterinary supervision.

✅ Key Benefits / Features

• Effectively reduces excessive thyroid hormone production
• Helps control symptoms such as weight loss, hyperactivity, and vomiting
• Supports stabilization prior to surgical intervention
• May improve cardiac and renal parameters affected by hyperthyroidism
• Convenient oral tablet formulation for accurate dosing

🧪 Ingredients

• Active Ingredient: Carbimazole – 5mg per tablet
• Inactive Ingredients (may vary by manufacturer):
  • Lactose monohydrate
  • Magnesium stearate
  • Maize starch
  • Hypromellose
  • Other standard tablet excipients

📊 Nutritional Composition / Active Ingredients

💊 Uses / Indications

• Cats:
  • Management of feline hyperthyroidism
  • Preoperative stabilization prior to thyroid surgery
  • Long-term control of thyroid hormone levels
• Dogs:
  • Rarely used; may be considered in cases of canine hyperthyroidism under specialist guidance

🐾 Feeding Instructions / Dosage

• Cats:
  • Typical starting dose: 5 mg orally twice daily
  • Adjust based on serum T4 levels and clinical response
• Dogs:
  • Starting dose: 10–15 mg orally once daily (based on body weight and thyroid hormone levels)
• Administration:
  • Can be given with or without food
  • If gastrointestinal upset occurs, administer with food
  • Do not crush or split tablets unless directed by a veterinarian
  • Regular monitoring of thyroid levels, renal function, and complete blood count is essential

⚠️ Possible Side Effects

• Common:
  • Vomiting
  • Inappetence
  • Lethargy
• Rare but serious:
  • Allergic reactions (facial swelling, rash, fever)
  • Jaundice or liver dysfunction
  • Blood cell abnormalities (e.g., leukopenia, thrombocytopenia)
  • Pruritus, alopecia, or self-induced trauma
• May unmask underlying renal disease due to reduced glomerular filtration rate

🔄 Drug & Food Interactions

• Avoid concurrent use with:
  • Iodine-restricted diets
  • Radioactive iodine therapy (discontinue carbimazole before treatment)
• May interact with:
  • Anticoagulants
  • Beta-blockers
  • Other antithyroid agents
• No significant food interactions reported; absorption may improve with food

• ⚠️ Precautions
• Not recommended for:
  • Pregnant or lactating animals
  • Pets with known hypersensitivity to carbimazole or methimazole
  • Animals with liver disease, diabetes mellitus, or autoimmune disorders
• Use with caution in pets with impaired kidney or liver function
• Monitor for delayed hypersensitivity reactions throughout treatment
• Store in a cool, dry place away from direct sunlight
• Keep out of reach of children and other animals