Overview
TOBREX® Sterile Ophthalmic Solution is a human-grade topical antibiotic eye drop manufactured by Novartis (Alcon). While formulated and FDA-approved for human use, it is widely prescribed extra-label by veterinarians to treat external bacterial eye infections in dogs and cats. Its active ingredient, Tobramycin, is a potent aminoglycoside antibiotic that provides broad-spectrum action against Gram-positive and Gram-negative ocular pathogens. It is commonly used for short-term management of bacterial conjunctivitis, keratitis, blepharitis, and secondary ocular infections.
Key Benefits / Features
✅ Broad-spectrum bactericidal action against common ocular pathogens
✅ Provides rapid relief from bacterial infection symptoms (redness, tearing, discharge)
✅ Sterile, clear solution formulation designed for gentle ocular administration
✅ Precise 5 mL dropper bottle for accurate dosing
✅ Commonly prescribed by veterinarians extra-label for canine and feline eye infections
Ingredients
Nutritional Composition / Active Ingredients
| Component |
Concentration per mL |
| Tobramycin |
3 mg (0.3%) |
| Benzalkonium chloride |
0.1 mg (0.01%) |
| Volume |
5 mL bottle |
Uses / Indications TOBREX® is indicated for:
-
Treatment of external bacterial eye infections (bacterial conjunctivitis, keratitis, blepharitis)
-
Post-operative prophylaxis following ocular surgery
-
Management of secondary bacterial eye infections in companion animals (off-label veterinary use)
Note: This product is not effective against viral, fungal, or non-bacterial ocular conditions.
-
Dosage & Administration:
-
Typical dosage: 1–2 drops into the affected eye(s) every 4–8 hours
-
In severe infections: 2 drops into the affected eye(s) every 1–2 hours initially until improvement, then reduced
-
Duration: As directed by your healthcare professional or veterinarian (typically 5–7 days)
-
Administration Tips: Wash hands before and after application. Avoid touching the dropper tip to the eye, skin, or any surface. (Note: Solution drops do not require shaking prior to use).
Possible Side Effects
-
Mild ocular stinging, burning, or discomfort upon application
-
Localized hypersensitivity (eyelid itching, eyelid swelling, conjunctival redness)
-
Risk of corneal fungal or non-susceptible bacterial superinfection with prolonged use
Drug & Food Interactions
-
No food interactions
-
Use with caution alongside systemic aminoglycoside antibiotics (e.g., gentamicin, amikacin) to avoid additive systemic toxicity
-
Separate administration of other topical eye medications by at least 5 minutes
Precautions
-
For external topical ophthalmic use only (not for injection)
-
Do not use in patients or animals with known hypersensitivity to tobramycin or aminoglycosides
-
Store between 15–25°C (59–77°F)
-
Keep tightly closed when not in use
-
Discard unused portion 28 days after opening
IMPORTANT NOTICE - THIS IS A PRESCRIPTION ONLY MEDICATION (POM)
POMs are stored and dispensed directly under licensed pharmacy or veterinary supervision.
As required by law, orders for this product will only be processed and delivered after our medical/veterinary team has verified a valid prescription and patient history.
